An artificial pancreas to fight type 1 diabetes
Diabeloop artificial pancreas integrates a telemedicine program, where patient glycemic data is sent. Thus, clinicians have access to patients data to modify treatment as necessary, for an improved long-term regulation.
In 2014, first clinical trials on 35 patients have shown a great success. Diabeloop artificial pancreas is still in development and should be on market before the end of 2017.
Type 1 diabetes
Type 1 diabetes is an autoimmune disease that affects 200,000 people in France, 30 million worldwide, and can strike anyone. It destroys the specific Pancreas cells that produce insulin, which regulates blood glucose levels. Half of the cases begin before age 20, as young as 1 year old. As a result patients have to manage diabetes their entire life.
To do that, these patients must prick their finger multiple times per day to measure their blood glucose levels, calculate their dose and inject insulin via a special syringe or with a pump.
Too much insulin leads to hypoglycemia, sometimes serious with a coma. Not enough insulin leads to hyperglycemia, which if repeated regularly brings serious complications (blindness, amputations, renal failure, heart diseases).
Every day diabetic patients must…
Calculate their base rates
In particular during the night, with the threat of nocturnal hypoglycemias.
Calculate the amount of insulin for their meals
Sugar and glucose in their meals has to be counted, and translated via a personal factor to a quantity of insulin.
Anticipate any physical activity
By reducing their base rate or take additional sugar. Without this, they will get an hypoglycemic event.
The solution: an artificial pancreas
the project started in 2011; a prototype was tested successfully on 35 patients in 2014
Fig 1. Example of the evolution of blood glucose in a diabetic patient with the usual treatment
Fig 2. Patient using Diabeloop
University hospital partners
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155 Cours Berriat